ART

Quitting smoking may improve ART outcomes for men and women
Source: Fertility and Sterility 2008; Advance

Evaluating the gender-specific impact of cigarette smoking on the outcomes of fertility treatment.

MedWire News : Research from Chile suggests that both men and women can improve their chances of successful fertility treatment by quitting smoking.

Ariel Fuentes ( University of Chile , Santiago ) and co-workers found that although cigarette smoking had no impact on implantation rates during assisted reproduction, it significantly reduced the number of retrieved ova, as well as the overall live birth rate.

The team studied 166 couples who were seeking to conceive via assisted reproductive technologies (ART). Recent active or passive cigarette smoking in women was assessed based on measurement serum and follicular fluid concentrations of continue, while male smoking was evaluated using interview data.

Recent exposure to tobacco smoke in women reduced the average number of retrieved ova from 9.6 to 7.8, a difference that was statistically significant after taking age and other potential confounding factors such as body mass index into account. In addition, male smoking conferred a significant reduction in live birth rate from 21 percent to 8 percent (relative risk=0.36).

“The substantial evidence of tobacco interference with ART demonstrates the need for medical or other forms of counseling in couples who smoke during IVF treatment,” the researchers conclude.

http://www.orgyn.com/en/news/2008/Week_46/Day_1/Quitting_smoking_may.asp?C=72954397637636689815